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Association of hypothyroidism with low-level arsenic exposure in rural West Texas.

Association of hypothyroidism with low-level arsenic exposure in rural West Texas.

Environ Res. 2015 Feb 23;138C:154-160

Authors: Gong G, Basom J, Mattevada S, Onger F

Abstract
It has been reported recently that a higher airborne arsenic level was correlated with higher urinary arsenic concentration and lower serum thyroxin level among urban policemen and rural highway workmen in Italy. The current study was to determine whether exposure to low-level arsenic groundwater (2-22µg/L) is associated with hypothyroidism among 723 participants (118 male and 267 female Hispanics; 108 male and 230 female non-Hispanic whites, NHW) living in rural West Texas counties. Arsenic and iodine levels in their groundwater used for drinking and or cooking were estimated by the inverse distance weighted (IDW) interpolation technique. Groundwater arsenic was ≥8µg/L in 36% of the subjects' wells while iodine concentration was <1µg/L in 91% of their wells. Logistic regression analysis showed that arsenic in groundwater ≥8µg/L and cumulative arsenic exposure (groundwater arsenic concentration multiplied by the number of years living in the current address) but not groundwater iodine concentration were significant predictors for hypothyroidism among Hispanics (p<0.05) but not NHW after adjusting for covariates such as age, gender, annual household income and health insurance coverage. The ethnic difference may be due to a marginally higher percentage of Hispanics (p=0.0622) who lived in areas with groundwater arsenic ≥8µg/L compared with NHW. The prevalence of hypothyroidism was significantly higher in Hispanics or NHW of this rural cohort than the national prevalence. Measures should be taken to reduce arsenic in drinking water in order to prevent hypothyroidism in rural areas.

PMID: 25721242 [PubMed - as supplied by publisher]

Efficacy of SMS text message interventions for smoking cessation: A meta-analysis.

Efficacy of SMS text message interventions for smoking cessation: A meta-analysis.

J Subst Abuse Treat. 2015 Feb 2;

Authors: Spohr SA, Nandy R, Gandhiraj D, Vemulapalli A, Anne S, Walters ST

Abstract
BACKGROUND: Mobile technology provides new opportunities for health promotion communication. The purpose of this study was to conduct a current and extensive meta-analytic review of SMS (short message service) text message-based interventions for individual smoking cessation.
METHODS: Academic Search Complete, PsycINFO, PubMed, and Scopus were reviewed for articles meeting selection criteria: 1) randomized controlled trials, 2) measured smoking cessation, and 3) intervention primarily delivered through SMS text messaging. Three and 6month follow-up of 7-day point prevalence or continuous abstinence was considered from studies meeting criteria. All analyses were conducted with intention-to-treat. Both fixed and random effects models were used to calculate the global outcome measure and confidence intervals.
RESULTS: Thirteen studies were identified that met inclusion criteria. The studies were found to be homogeneous [Q12=10.89, p=0.54]. Odds ratios based on the random effects models suggested that interventions generally increased quit rates compared to controls, 1.35 [95% CI=1.23, 1.48]. Intervention efficacy was higher in studies with a 3month follow-up compared to 6month follow-up. Text plus programs (e.g., text messaging plus Web or in-person intervention modalities) performed only slightly better than text only programs. Pooled results also indicate message frequency schedule can affect quit rates, in which fixed schedules performed better than decreasing or variable schedules. The use of quit status assessment messages was not related to intervention efficacy.
CONCLUSION: Smoking quit rates for the text messaging intervention group were 35% higher compared to the control group quit rates. Results suggest that SMS text messaging may be a promising way to improve smoking cessation outcomes. This is significant given the relatively wide reach and low cost of text message interventions. Identifying the components that make interventions efficacious will help to increase the effectiveness of such interventions.

PMID: 25720333 [PubMed - as supplied by publisher]

Association of hypothyroidism with low-level arsenic exposure in rural West Texas

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Gong, G. | Basom, J. | Mattevada, S. | Onger, F.
Publication year: 2015
Journal / Book title: Environmental Research

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Cancer mortality in the meat and delicatessen departments of supermarkets (1950-2006)

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Johnson, E.S. | Cardarelli, K. | Jadhav, S. | Chedjieu, I.P. | Faramawi, M. | Fischbach, L. | Ndetan, H. | Wells, T.L.-C. | Patel, K.V. | Katyal, A.
Publication year: 2015
Journal / Book title: Environment International

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Arsenic exposure, hyperuricemia, and gout in US adults

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Kuo, C.-C. | Weaver, V. | Fadrowski, J.J. | Lin, Y.-S. | Guallar, E. | Navas-Acien, A.
Publication year: 2015
Journal / Book title: Environment International

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High therapeutic potential of positive allosteric modulation of α7 nAChRs in a rat model of traumatic brain injury: Proof-of-concept

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Gatson, J.W. | Simpkins, J.W. | Uteshev, V.V.
Publication year: 2015
Journal / Book title: Brain Research Bulletin

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AMPA receptor desensitization is the determinant of AMPA receptor mediated excitotoxicity in purified retinal ganglion cells

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Park, Y.H. | Mueller, B.H. | McGrady, N.R. | Ma, H.-Y. | Yorio, T.
Publication year: 2015
Journal / Book title: Experimental Eye Research

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Development of biodegradable nanocarriers loaded with a monoclonal antibody

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Gdowski, A. | Ranjan, A. | Mukerjee, A. | Vishwanatha, J.
Publication year: 2015
Journal / Book title: International Journal of Molecular Sciences

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Synthesis, pharmacological evaluation and molecular modeling studies of triazole containing dopamine D3 receptor ligands

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Peng, X. | Wang, Q. | Mishra, Y. | Xu, J. | Reichert, D.E. | Malik, M. | Taylor, M. | Luedtke, R.R. | Mach, R.H.
Publication year: 2015
Journal / Book title: Bioorganic and Medicinal Chemistry Letters

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Neuroglobin Overexpression Inhibits AMPK Signaling and Promotes Cell Anabolism

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Cai, B. | Li, W. | Mao, X. | Winters, A. | Ryou, M.-G. | Liu, R. | Greenberg, D.A. | Wang, N. | Jin, K. | Yang, S.-H.
Publication year: 2015
Journal / Book title: Molecular Neurobiology

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Elephant (Elephas maximus) health and management in Asia: Variations in veterinary perspectives

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Miller, D. | Jackson, B. | Riddle, H.S. | Stremme, C. | Schmitt, D. | Miller, T.
Publication year: 2015
Journal / Book title: Veterinary Medicine International

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Interaction between Nef and INI1/SMARCB1 augments replicability of HIV-1 in resting human peripheral blood mononuclear cells

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Pyeon, D. | Park, I.-W.
Publication year: 2015
Journal / Book title: Archives of Virology

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Rarity of the alzheimer disease-protective APP A673T variant in the United States

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Wang, L.-S. | Naj, A.C. | Graham, R.R. | Crane, P.K. | Kunkle, B.W. | Cruchaga, C. | Gonzalez Murcia, J.D. | Cannon-Albright, L. | Baldwin, C.T. | Zetterberg, H. | Blennow, K. | Kukull, W.A. | Faber, K.M. | Schupf, N. | Norton, M.C. | Tschanz, J.T. | Munger, R.G. | Corcoran, C.D. | Rogaeva, E. | Albert, M.S. | Albin, R.L. | Apostolova, L.G. | Arnold, S.E. | Barber, R. | Barmada, M.M. | Barnes, L.L. | Beach, T.G. | Becker, J.T. | Beecham, G.W. | Beekly, D. | Bennett, D.A. | Bigio, E.H. | Bird, T.D. | Blacker, D. | Boeve, B.F. | Bowen, J.D. | Boxer, A. | Burke, J.R. | Buxbaum, J.D. | Cairns, N.J. | Cao, C. | Carlson, C.S. | Carroll, S.L. | Chui, H.C. | Clark, D.G. | Cribbs, D.H. | Crocco, E.A. | DeCarli, C. | DeKosky, S.T. | Demirci, F.Y. | Dick, M. | Dickson, D.W. | Duara, R. | Ertekin-Taner, N. | Fallon, K.B. | Farlow, M.R. | Ferris, S. | Frosch, M.P. | Galasko, D.R. | Ganguli, M. | Gearing, M. | Geschwind, D.H. | Ghetti, B. | Gilbert, J.R. | Glass, J.D. | Graff-Radford, N.R. | Growdon, J.H. | Hamilton, R.L. | Hamilton-Nelson, K.L. | Harrell, L.E. | Head, E. | Honig, L.S. | Hulette, C.M. | Hyman, B.T. | Jarvik, G.P. | Jicha, G.A. | Jin, L.-W. | Jun, G. | Kamboh, M.I. | Karydas, A. | Kaye, J.A. | Kim, R. | Koo, E.H. | Kowall, N.W. | Kramer, J.H. | Kramer, P. | LaFerla, F.M. | Lah, J.J. | Leverenz, J.B. | Levey, A.I. | Li, G. | Lieberman, A.P. | Lopez, O.L. | Lunetta, K.L. | Lyketsos, C.G. | Mack, W.J. | Marson, D.C. | Martin, E.R. | Martiniuk, F. | Mash, D.C. | Masliah, E. | McCormick, W.C. | McCurry, S.M. | McDavid, A.N. | McKee, A.C. | Mesulam, M.M. | Miller, B.L. | Miller, C.A. | Miller, J.W. | Montine, T.J. | Morris, J.C. | Murrell, J.R. | Olichney, J.M. | Parisi, J.E. | Perry, W. | Peskind, E. | Petersen, R.C. | Pierce, A. | Poon, W.W. | Potter, H. | Quinn, J.F. | Raj, A. | Raskind, M. | Reiman, E.M. | Reisberg, B. | Reitz, C. | Ringman, J.M. | Roberson, E.D. | Rosen, H.J. | Rosenberg, R.N. | Sano, M. | Saykin, A.J. | Schneider, J.A. | Schneider, L.S. | Seeley, W.W. | Smith, A.G. | Sonnen, J.A. | Spina, S. | Stern, R.A. | Tanzi, R.E. | Thornton-Wells, T.A. | Trojanowski, J.Q. | Troncoso, J.C. | Tsuang, D.W. | Van Deerlin, V.M. | Van Eldik, L.J. | Vardarajan, B.N. | Vinters, H.V. | Vonsattel, J.P. | Weintraub, S. | Welsh-Bohmer, K.A. | Williamson, J. | Wishnek, S. | Woltjer, R.L. | Wright, C.B. | Younkin, S.G. | Yu, C.-E. | Yu, L. | Lin, C.-F. | Dombroski, B.A. | Cantwell, L.B. | Partch, A. | Valladares, O. | Hakonarson, H. | St George-Hyslop, P. | Green, R.C. | Goate, A.M. | Foroud, T.M. | Carney, R.M. | Larson, E.B. | Behrens, T.W. | Kauwe, J.S.K. | Haines, J.L. | Farrer, L.A. | Pericak-Vance, M.A. | Mayeux, R. | Schellenberg, G.D.
Publication year: 2015
Journal / Book title: JAMA Neurology

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Steady state and time resolved fluorescence studies of azadioxatriangulenium (ADOTA) fluorophore in silica and PVA thin films

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Chib, R. | Raut, S. | Shah, S. | Grobelna, B. | Akopova, I. | Rich, R. | Sørensen, T.J. | Laursen, B.W. | Grajek, H. | Gryczynski, Z. | Gryczynski, I.
Publication year: 2015
Journal / Book title: Dyes and Pigments

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Chronic Pain and Health Care Spending: An Analysis of Longitudinal Data from the Medical Expenditure Panel Survey

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Stockbridge, E.L. | Suzuki, S. | Pagán, J.A.
Publication year: 2015
Journal / Book title: Health Services Research

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Aberrant histone acetylation promotes mitochondrial respiratory suppression in the brain of alcoholic rats

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Jung, M.E. | Metzger, D.B.
Publication year: 2015
Journal / Book title: Journal of Pharmacology and Experimental Therapeutics

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A depressive endophenotype of poorer cognition among cognitively healthy community-dwelling adults: Results from the Western Australia memory study

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Johnson, L.A. | Sohrabi, H.R. | Hall, J.R. | Kevin, T. | Edwards, M. | O'Bryant, S.E. | Martins, R.N.
Publication year: 2015
Journal / Book title: International Journal of Geriatric Psychiatry

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[2] Commentaries on Viewpoint: The ongoing need for good physiological investigation: Obstructive sleep apnea in HIV patients as a paradigm

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Jouett, N.P. | Smith, M.L.
Publication year: 2015
Journal / Book title: Journal of Applied Physiology

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Determination of thailandepsin B in rat plasma with a LC-MS/MS method

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Cheng, Z. | Ding, L. | Zhang, Y. | Chen, G. | Chen, C. | Cheng, Y.-Q. | Jiang, H.
Publication year: 2015
Journal / Book title: Bioanalysis

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HIV-1 tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: Implications for HIV-associated neurocognitive disorders

Latest UNTHSC Articles in Scopus - Sat, 02/28/2015 - 7:31pm
Author(s):Fields, J. | Dumaop, W. | Elueteri, S. | Campos, S. | Serger, E. | Trejo, M. | Kosberg, K. | Adame, A. | Spencer, B. | Rockenstein, E. | He, J.J. | Masliah, E.
Publication year: 2015
Journal / Book title: Journal of Neuroscience

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