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Observational Study Fails to Demonstrate the Effectiveness of OMT in Decreasing Low Back Pain.

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Observational Study Fails to Demonstrate the Effectiveness of OMT in Decreasing Low Back Pain.

J Am Osteopath Assoc. 2014 Nov;114(11):e119-20

Authors: Licciardone JC

PMID: 25352411 [PubMed - in process]

Impact of a community based implementation of REACH II program for caregivers of Alzheimer's patients.

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Impact of a community based implementation of REACH II program for caregivers of Alzheimer's patients.

PLoS One. 2014;9(2):e89290

Authors: Lykens K, Moayad N, Biswas S, Reyes-Ortiz C, Singh KP

Abstract
BACKGROUND: In 2009 an estimated 5.3 million people in the United States were afflicted with Alzheimer's disease, a degenerative form of dementia. The impact of this disease is not limited to the patient but also has significant impact on the lives and health of their family caregivers. The Resources for Enhancing Alzheimer's Caregiver Health (REACH II) program was developed and tested in clinical studies. The REACH II program is now being delivered by community agencies in several locations. This study examines the impact of the REACH II program on caregiver lives and health in a city in north Texas.
STUDY DESIGN: Family caregivers of Alzheimer's patients were assessed using an instrument covering the multi-item domains of Caregiver Burden, Depression, Self-Care, and Social Support upon enrollment in the program and at the completion of the 6 month intervention. The domain scores were analyzed using a multivariate paired t-test and Bonferroni confidence interval for the differences in pre- and post-service domain scores.
RESULTS: A total of 494 families were enrolled in the program during the period January 1, 2011 through June 30, 2012. Of these families 177 completed the 6 month program and have pre - and post service domain scores. The median age for the caregivers was 62 years. The domain scores for Depression and Caregiver Burden demonstrated statistically significant improvements upon program completion.
CONCLUSION: The REACH II intervention was successfully implemented by a community agency with comparable impacts to those of the clinical trial warranting wider scale implementation.

PMID: 24586664 [PubMed - indexed for MEDLINE]

Characterization and reduction of cardiac- and respiratory-induced noise as a function of the sampling rate (TR) in fMRI.

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Characterization and reduction of cardiac- and respiratory-induced noise as a function of the sampling rate (TR) in fMRI.

Neuroimage. 2014 Apr 1;89:314-30

Authors: Cordes D, Nandy RR, Schafer S, Wager TD

Abstract
It has recently been shown that both high-frequency and low-frequency cardiac and respiratory noise sources exist throughout the entire brain and can cause significant signal changes in fMRI data. It is also known that the brainstem, basal forebrain and spinal cord areas are problematic for fMRI because of the magnitude of cardiac-induced pulsations at these locations. In this study, the physiological noise contributions in the lower brain areas (covering the brainstem and adjacent regions) are investigated and a novel method is presented for computing both low-frequency and high-frequency physiological regressors accurately for each subject. In particular, using a novel optimization algorithm that penalizes curvature (i.e. the second derivative) of the physiological hemodynamic response functions, the cardiac- and respiratory-related response functions are computed. The physiological noise variance is determined for each voxel and the frequency-aliasing property of the high-frequency cardiac waveform as a function of the repetition time (TR) is investigated. It is shown that for the brainstem and other brain areas associated with large pulsations of the cardiac rate, the temporal SNR associated with the low-frequency range of the BOLD response has maxima at subject-specific TRs. At these values, the high-frequency aliased cardiac rate can be eliminated by digital filtering without affecting the BOLD-related signal.

PMID: 24355483 [PubMed - indexed for MEDLINE]

Coding ill-defined and unknown cause of death is 13 times more frequent in Denmark than in Finland

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Ylijoki-Sørensen, S. | Sajantila, A. | Lalu, K. | Bøggild, H. | Boldsen, J.L. | Boel, L.W.T.
Publication year: 2014
Journal / Book title: Forensic Science International

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Autopsy rate in suicide is low among elderly in Denmark compared with Finland

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Ylijoki-Sørensen, S. | Boldsen, J.L. | Boel, L.W.T. | Bøggild, H. | Lalu, K. | Sajantila, A.
Publication year: 2014
Journal / Book title: Forensic Science International

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Methylene blue promotes quiescence of rat neural progenitor cells

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Xie, L. | Choudhury, G.R. | Wang, J. | Park, Y. | Liu, R. | Yuan, F. | Zhang, C.-L. | Yorio, T. | Jin, K. | Yang, S.-H.
Publication year: 2014
Journal / Book title: Frontiers in Cellular Neuroscience

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Discriminative and locomotor effects of five synthetic cathinones in rats and mice

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Gatch, M.B. | Rutledge, M.A. | Forster, M.J.
Publication year: 2014
Journal / Book title: Psychopharmacology

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In vivo assessment of smt 19969 in a hamster model of clostridium difficile infection

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Weiss, W. | Pulse, M. | Vickers, R.
Publication year: 2014
Journal / Book title: Antimicrobial Agents and Chemotherapy

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Indoor air pollution from solid fuels and peripheral Blood DNA methylation: Findings from a population study in Warsaw, Poland

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Tao, M.-H. | Zhou, J. | Rialdi, A.P. | Martinez, R. | Dabek, J. | Scelo, G. | Lissowska, J. | Chen, J. | Boffetta, P.
Publication year: 2014
Journal / Book title: Environmental Research

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Pregnancy Research on Osteopathic Manipulation Optimizing Treatment Effects: the PROMOTE study

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Hensel, K.L. | Buchanan, S. | Brown, S.K. | Rodriguez, M. | Cruser, d.A.
Publication year: 2014
Journal / Book title: American Journal of Obstetrics and Gynecology

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Using modified approaches on marginal regression analysis of longitudinal data with time-dependent covariates

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Zhou, Y. | Lefante, J. | Rice, J. | Chen, S.
Publication year: 2014
Journal / Book title: Statistics in Medicine

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Unsilencing voices: a study of zoo signs and their language of authority

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Fogelberg, K.
Publication year: 2014
Journal / Book title: Cultural Studies of Science Education

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Molecular genetic investigative leads to differentiate monozygotic twins

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Budowle, B.
Publication year: 2014
Journal / Book title: Investigative Genetics

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PTEN degradation after ischemic stroke: A double-edged sword

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Li, W. | Huang, R. | Chen, Z. | Yan, L.-J. | Simpkins, J.W. | Yang, S.-H.
Publication year: 2014
Journal / Book title: Neuroscience

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Characterization of [3H]LS-3-134, a novel arylamide phenylpiperazine D3 dopamine receptor selective radioligand

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Rangel-Barajas, C. | Malik, M. | Taylor, M. | Neve, K.A. | Mach, R.H. | Luedtke, R.R.
Publication year: 2014
Journal / Book title: Journal of Neurochemistry

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What Role Does Sleep Play in Weight Gain in the First Semester of University?

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Roane, B.M. | Seifer, R. | Sharkey, K.M. | Van Reen, E. | Bond, T.L.Y. | Raffray, T. | Carskadon, M.A.
Publication year: 2014
Journal / Book title: Behavioral Sleep Medicine

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Platinum(IV) cisplatin derivative trans, cis, cis-bis(heptanoato)amine(cyclohexylamine)dichloridoplatinum(IV) has an enhanced therapeutic index compared to cisplatin for the treatment of non-small cell lung cancer

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Shi, Y. | Koneru, B. | Redfearn, W. | Miller, M.L. | Myers, L. | Di Pasqua, A.J.
Publication year: 2014
Journal / Book title: Inorganica Chimica Acta

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A useful mouse model of glucocorticoid-induced ocular hypertension

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Clark, A.F.
Publication year: 2014
Journal / Book title: Investigative Ophthalmology and Visual Science

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Neuronal injury from cardiac arrest: aging years in minutes

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Cherry, B.H. | Sumien, N. | Mallet, R.T.
Publication year: 2014
Journal / Book title: AGE

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Capsule Commentary on Albrecht et al., Hospital Discharge Instructions: Comprehension and Compliance Among Older Adults

Latest UNTHSC Articles in Scopus - Thu, 10/30/2014 - 12:06pm
Author(s):Tak, H.J.
Publication year: 2014
Journal / Book title: Journal of General Internal Medicine

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