Recent Research Articles from UNTHSC

Recent research articles indexed in PubMed from authors affiliated with the UNT Health Science Center.

Subscribe to Recent Research Articles from UNTHSC  feed Recent Research Articles from UNTHSC
NCBI: db=pubmed; Term="University of North Texas Health Science Center"[All Fields] OR "Univ. of North Texas Health Science Center"[All Fields] OR "UNT Health Science Center"[All Fields] OR "Osteopathic Research Center"[All Fields] OR "University of North Texas System College of Pharmacy"[All Fields] OR "UNT System College of Pharmacy"[All Fields] OR "College of Pharmacy, University of North Texas System"[All Fields]
Updated: 2 hours 41 min ago

The Effects of Performance Fatigability on Postural Control and Rehabilitation in the Older Patient.

Mon, 02/06/2017 - 07:34
Related Articles

The Effects of Performance Fatigability on Postural Control and Rehabilitation in the Older Patient.

Curr Geriatr Rep. 2016 Sep;5(3):172-178

Authors: Papa EV, Hassan M, Bugnariu N

Abstract
Fatigue is common in older adults and has a significant effect on quality of life. Despite the high prevalence of fatigue in older individuals, several aspects are poorly understood. It is important to differentiate subjective fatigue complaints from fatigability of motor performance because the two are independent constructs with potentially distinct consequences on mobility. Performance fatigability is the magnitude of change in a performance criterion over a given time of task performance. Performance fatigability is a compulsory element of any strength training program, yet strength training is an important component of rehabilitation programs for older adults. The consequences of fatigability for older adults suggest that acute exercise of various types may result in acute impairments in postural control. The effects of performance fatigability on postural control in older adults are evaluated here to aid the rehabilitation clinician in making recommendations for evaluation of fall risks and exercise prescription.

PMID: 28154794 [PubMed - in process]

Potential Problems With Systematic Reviews and Meta-Analyses.

Mon, 02/06/2017 - 07:34
Related Articles

Potential Problems With Systematic Reviews and Meta-Analyses.

J Pain. 2017 Feb;18(2):228-229

Authors: Gatchel RJ, Licciardone JC

PMID: 28153422 [PubMed - in process]

Non-Gradient Blue Native Polyacrylamide Gel Electrophoresis.

Fri, 02/03/2017 - 16:52

Non-Gradient Blue Native Polyacrylamide Gel Electrophoresis.

Curr Protoc Protein Sci. 2017 Feb 02;87:19.29.1-19.29.12

Authors: Luo X, Wu J, Jin Z, Yan LJ

Abstract
Gradient blue native polyacrylamide gel electrophoresis (BN-PAGE) is a well established and widely used technique for activity analysis of high-molecular-weight proteins, protein complexes, and protein-protein interactions. Since its inception in the early 1990s, a variety of minor modifications have been made to this gradient gel analytical method. Here we provide a major modification of the method, which we call non-gradient BN-PAGE. The procedure, similar to that of non-gradient SDS-PAGE, is simple because there is no expensive gradient maker involved. The non-gradient BN-PAGE protocols presented herein provide guidelines on the analysis of mitochondrial protein complexes, in particular, dihydrolipoamide dehydrogenase (DLDH) and those in the electron transport chain. Protocols for the analysis of blood esterases or mitochondrial esterases are also presented. The non-gradient BN-PAGE method may be tailored for analysis of specific proteins according to their molecular weight regardless of whether the target proteins are hydrophobic or hydrophilic. © 2017 by John Wiley & Sons, Inc.

PMID: 28150881 [PubMed - in process]

Adequate dietary fiber supplement along with TONE concept can help avoid surgery in most patients with advanced hemorrhoids.

Fri, 02/03/2017 - 16:52
Related Articles

Adequate dietary fiber supplement along with TONE concept can help avoid surgery in most patients with advanced hemorrhoids.

Minerva Gastroenterol Dietol. 2017 Feb 01;:

Authors: Garg P, Singh P

Abstract
BACKGROUND: The root cause of hemorrhoids are three deranged defecation habits (DDH) - (1) increased straining, (2) prolonged defecation-time and, (3) frequent bowel-motions. These DDH are responsible for development of new hemorrhoids, progression of existing hemorrhoids and hemorrhoidal rupture (bleeding). DDH can be corrected by TONE concept. TONE entails specifying exact treatment goals (T-Three minutes at defecation, O-Once a day defecation- frequency, N-No straining during passing motions, E-Enough fiber). TONE can be implemented by proper counseling and by prescribing fiber supplement appropriately (5-6 teaspoonfuls of psyllium husk with 600 ml of water daily). Corrected DDH would prevent the progression of hemorrhoids and bleeding. An office procedure may be done to further downgrade the hemorrhoids.
METHODS: Patients with advanced hemorrhoids (grade III & IV) who were referred for surgery were prescribed fiber supplement and were counseled to follow TONE. The outcome parameters evaluated were- improvement in prolapse, bleeding episodes, satisfaction levels.
RESULTS: 102 patients (Male/Female: 75/10, age 46.0 ±13.5 years, 17 lost to follow-up) with advanced hemorrhoids (grades: early III-41, late III-38 & IV-6) were included in the study. All patients had symptoms of prolapsed and bleeding was present in 71.8% (61/85) patients. After the follow-up of 40 (12-96) months, 68.2% (58/85) patients were highly satisfied, 12.9% (11/85) were moderately satisfied and 18.9% (16/85) were not satisfied with treatment. Prolapse improved in 56.5%(48/85), didn't progress over time in 25.9(22/85) and continued to progress in 4.7 %(4/85) patients. 12.9% (11/85) underwent operation for hemorrhoids. Bleeding episodes decreased from 71.8% (61/85) to 29.4%(25/85) (p<0.0001,Fischer's).
CONCLUSIONS: Adequate fiber supplement coupled with TONE concept can correct deranged defecation habits and can thus prevent progression of hemorrhoids and bleeding and the need for surgery in most patients with advanced hemorrhoids.

PMID: 28150480 [PubMed - as supplied by publisher]

Pages