Gibson D. Lewis Library

Feed aggregator

Clear Cell "Sugar" Tumor of the Lung: Benign or Malignant?

Recent Research Articles from UNTHSC - Wed, 05/27/2015 - 11:28pm

Clear Cell "Sugar" Tumor of the Lung: Benign or Malignant?

Int Surg. 2015 May;100(5):924-926

Authors: Olivencia-Yurvati AH, Rodriguez AE

Abstract
Clear cell "sugar" tumors of the lung are rare pulmonary tumors. This case study illustrates a patient who was found to have a persistent nodule in the left-upper lobe of the lung. Positron emission tomographic scanning showed mild-moderate 18-fluorodeoxyglucose uptake. Based on these findings, a video-assisted resection of the tumor was undertaken. The mass was identified histologically, as a clear cell "sugar" tumor of the lung. This case report discusses the benign versus malignant nature of this rare tumor.

PMID: 26011217 [PubMed - as supplied by publisher]

Chest pain · shortness of breath · fever and nausea · Dx?

Recent Research Articles from UNTHSC - Wed, 05/27/2015 - 11:28pm

Chest pain · shortness of breath · fever and nausea · Dx?

J Fam Pract. 2015 May;64(5):282-4

Authors: Manov A, Gopalakrishnan PP, Subramaniam S, Wardi M, White J

Abstract
A 38-year-old Hispanic man was brought to the emergency department after losing consciousness and falling at home, striking his elbow, head, and neck. For the past week, he'd had palpitations, shortness of breath, mild swelling of the lower extremities, fever, nausea, and fatigue. He had also been experiencing squeezing chest pain that worsened with exertion and was only partially relieved by nitroglycerin.

PMID: 26009736 [PubMed - in process]

Motivational tools to improve probationer treatment outcomes.

Recent Research Articles from UNTHSC - Wed, 05/27/2015 - 11:28pm

Motivational tools to improve probationer treatment outcomes.

Contemp Clin Trials. 2015 May 22;

Authors: Taxman FS, Walters ST, Sloas LB, Lerch J, Rodriguez M

Abstract
BACKGROUND: Motivational interviewing (MI) is a promising practice to increase motivation, treatment retention, and reducing recidivism among offender populations. Computer-delivered interventions have grown in popularity as a way to change behaviors associated with drug and alcohol use.
METHODS/DESIGN: Motivational Assistance Program to Initiate Treatment (MAPIT) is a three arm, multisite, randomized controlled trial, which examines the impact of Motivational Interviewing (MI), a Motivational Computer Program (MC), and Supervision as Usual (SAU) on addiction treatment initiation, engagement, and retention. Secondary outcomes include drug/alcohol use, probation progress, recidivism (i.e., criminal behavior) and HIV/AIDS testing and treatment among probationers. Participant characteristics are measured at baseline, 2, and 6months after assignment. The entire study will include 600 offenders, with each site recruiting 300 offenders (Baltimore City, Maryland and Dallas, Texas). All participants will go through standard intake procedures for probation and participate in probation requirements as usual. After standard intake, participants will be recruited and screened for eligibility.
DISCUSSION: The results of this clinical trial will fill a gap in knowledge about ways to motivate probationers to participate in addiction treatment and HIV care. This randomized clinical trial is innovative in the way it examines the use of in-person vs. technological approaches to improve probationer success.
TRIAL REGISTRATION: NCT01891656.

PMID: 26009023 [PubMed - as supplied by publisher]

Selective chemoprecipitation to enrich nitropeptides from complex proteomes for mass-spectrometric analysis.

Recent Research Articles from UNTHSC - Wed, 05/27/2015 - 11:28pm
Related Articles

Selective chemoprecipitation to enrich nitropeptides from complex proteomes for mass-spectrometric analysis.

Nat Protoc. 2014 Apr;9(4):882-95

Authors: Prokai L, Guo J, Prokai-Tatrai K

Abstract
Post-translational protein nitration has attracted interest owing to its involvement in cellular signaling, effects on protein function and potential as biomarker of nitroxidative stress. We describe a procedure for enriching nitropeptides for mass spectrometry (MS)-based proteomics that is a simple and reliable alternative to immunoaffinity-based methods. The starting material for this procedure is a proteolytic digest. The peptides are reacted with formaldehyde and sodium cyanoborohydride to dimethylate all the N-terminal and side chain amino groups. Sodium dithionite is added subsequently to reduce the nitro groups to amines; in theory, the only amino groups present will have originally been nitro groups. The peptide sample is then applied to a solid-phase active ester reagent (SPAER), and those peptides with amino groups will be selectively and covalently captured. Release of the peptides on hydrolysis with trifluoroacetic acid (TFA) results in peptides that have a 4-formyl-benzamido group where the nitro group used to be. In qualitative setups, the procedure can be used to identify proteins modified by reactive nitrogen species and to determine the specific sites of their nitration. Quantitative measurements can be performed by stable-isotope labeling of the peptides in the reductive dimethylation step. Preparation of the SPAER takes about 1 d. Enrichment of nitropeptides requires about 2 d, and sample preparations need 1-30 h, depending on the experimental design. LC-MS/MS assays take from 4 h to several days and data processing can be done in 1-7 d.

PMID: 24651500 [PubMed - indexed for MEDLINE]

A pilot case-cohort study of brain cancer in poultry and control workers.

Recent Research Articles from UNTHSC - Wed, 05/27/2015 - 11:28pm
Related Articles

A pilot case-cohort study of brain cancer in poultry and control workers.

Nutr Cancer. 2014;66(3):343-50

Authors: Gandhi S, Felini MJ, Ndetan H, Cardarelli K, Jadhav S, Faramawi M, Johnson ES

Abstract
We conducted an exploratory study to investigate which exposures (including poultry oncogenic viruses) are associated with brain cancer in poultry workers. A total of 46,819 workers in poultry and nonpoultry plants from the same union were initially followed for mortality. Brain cancer was observed to be in excess among poultry workers. Here we report on a pilot case-cohort study with cases consisting of 26 (55%) of the 47 brain cancer deaths recorded in the cohort, and controls consisting of a random sample of the cohort (n = 124). Exposure information was obtained from telephone interviews, and brain cancer mortality risk estimated by odds ratios. Increased risk of brain cancer was associated with killing chickens, odds ratio (OR) = 5.8 (95% confidence interval, 1.2-28.3); working in a shell-fish farm, OR = 13.0 (95% CI, 1.9-84.2); and eating uncooked fish, OR = 8.2 (95% CI, 1.8-37.0). Decreased risks were observed for chicken pox illness, OR = 0.2 (95% CI, 0.1-0.6), and measles vaccination, OR = 0.2 (95% CI, 0.1-0.6). Killing chickens, an activity associated with the highest occupational exposure to poultry oncogenic viruses, was associated with brain cancer mortality, as were occupational and dietary shellfish exposures. These findings are novel.

PMID: 24564367 [PubMed - indexed for MEDLINE]

Therapeutic potential of cancer stem cells

Latest UNTHSC Articles in Scopus - Wed, 05/27/2015 - 11:28am
Author(s):Yang, C. | Jin, K. | Tong, Y. | Cho, W.C.
Publication year: 2015
Journal / Book title: Medical Oncology

Access all results for your search in Scopus

Total testosterone and neuropsychiatric symptoms in elderly men with Alzheimer's disease

Latest UNTHSC Articles in Scopus - Wed, 05/27/2015 - 11:28am
Author(s):Hall, J.R. | Wiechmann, A.R. | Cunningham, R.L. | Johnson, L.A. | Edwards, M. | Barber, R.C. | Singh, M. | Winter, S. | O'Bryant, S.E.
Publication year: 2015
Journal / Book title: Alzheimer's Research and Therapy

Access all results for your search in Scopus

The effects of sigma (σ1) receptor-selective ligands on muscarinic receptor antagonist-induced cognitive deficits in mice

Latest UNTHSC Articles in Scopus - Wed, 05/27/2015 - 11:28am
Author(s):Malik, M. | Rangel-Barajas, C. | Sumien, N. | Su, C. | Singh, M. | Chen, Z. | Huang, R.-Q. | Meunier, J. | Maurice, T. | Mach, R.H. | Luedtke, R.R.
Publication year: 2015
Journal / Book title: British Journal of Pharmacology

Access all results for your search in Scopus

Exosomes are unlikely involved in intercellular Nef transfer

Latest UNTHSC Articles in Scopus - Wed, 05/27/2015 - 11:28am
Author(s):Luo, X. | Fan, Y. | Park, I.-W. | He, J.J.
Publication year: 2015
Journal / Book title: PLoS ONE

Access all results for your search in Scopus

Neonatal variables, altitude of residence and Aymara Ancestry in Northern Chile

Latest UNTHSC Articles in Scopus - Wed, 05/27/2015 - 11:28am
Author(s):Rothhammer, F. | Fuentes-Guajardo, M. | Chakraborty, R. | Bermejo, J.L. | Dittmar, M.
Publication year: 2015
Journal / Book title: PLoS ONE

Access all results for your search in Scopus

C-Jun NH<inf>2</inf>-terminal kinase-induced proteasomal degradation of c-FLIP<inf>L/S</inf> and Bcl<inf>2</inf> sensitize prostate cancer cells to Fas- and mitochondria-mediated apoptosis by tetrandrine

Latest UNTHSC Articles in Scopus - Wed, 05/27/2015 - 11:28am
Author(s):Chaudhary, P. | Vishwanatha, J.K.
Publication year: 2015
Journal / Book title: Biochemical Pharmacology

Access all results for your search in Scopus

Activation of mTOR: A culprit of Alzheimer’s disease?

Latest UNTHSC Articles in Scopus - Wed, 05/27/2015 - 11:28am
Author(s):Cai, Z. | Chen, G. | He, W. | Xiao, M. | Yan, L.-J.
Publication year: 2015
Journal / Book title: Neuropsychiatric Disease and Treatment

Access all results for your search in Scopus

Methylene blue protects astrocytes against glucose oxygen deprivation by improving cellular respiration

Latest UNTHSC Articles in Scopus - Wed, 05/27/2015 - 11:28am
Author(s):Choudhury, G.R. | Winters, A. | Rich, R.M. | Ryou, M.-G. | Gryczynski, Z. | Yuan, F. | Yang, S.-H. | Liu, R.
Publication year: 2015
Journal / Book title: PLoS ONE

Access all results for your search in Scopus

Coupling between arterial pressure, cerebral blood velocity, and cerebral tissue oxygenation with spontaneous and forced oscillations

Latest UNTHSC Articles in Scopus - Wed, 05/27/2015 - 11:28am
Author(s):Rickards, C.A. | Sprick, J.D. | Colby, H.B. | Kay, V.L. | Tzeng, Y.-C.
Publication year: 2015
Journal / Book title: Physiological Measurement

Access all results for your search in Scopus

Association of hypothyroidism with low-level arsenic exposure in rural West Texas

Latest UNTHSC Articles in Scopus - Wed, 05/27/2015 - 11:28am
Author(s):Gong, G. | Basom, J. | Mattevada, S. | Onger, F.
Publication year: 2015
Journal / Book title: Environmental Research

Access all results for your search in Scopus

Cancer mortality in the meat and delicatessen departments of supermarkets (1950-2006)

Latest UNTHSC Articles in Scopus - Wed, 05/27/2015 - 11:28am
Author(s):Johnson, E.S. | Cardarelli, K. | Jadhav, S. | Chedjieu, I.P. | Faramawi, M. | Fischbach, L. | Ndetan, H. | Wells, T.L.-C. | Patel, K.V. | Katyal, A.
Publication year: 2015
Journal / Book title: Environment International

Access all results for your search in Scopus

A population-based study of incidence and patient survival of small cell carcinoma in the United States, 1992-2010

Latest UNTHSC Articles in Scopus - Wed, 05/27/2015 - 11:28am
Author(s):Dores, G.M. | Qubaiah, O. | Mody, A. | Ghabach, B. | Devesa, S.S.
Publication year: 2015
Journal / Book title: BMC Cancer

Access all results for your search in Scopus

Transcription Factor Brn-3b Overexpression Enhances Neurite Outgrowth in PC12 Cells Under Condition of Hypoxia

Latest UNTHSC Articles in Scopus - Wed, 05/27/2015 - 11:28am
Author(s):Phatak, N.R. | Stankowska, D.L. | Krishnamoorthy, R.R.
Publication year: 2015
Journal / Book title: Cellular and Molecular Neurobiology

Access all results for your search in Scopus

Arsenic exposure, hyperuricemia, and gout in US adults

Latest UNTHSC Articles in Scopus - Wed, 05/27/2015 - 11:28am
Author(s):Kuo, C.-C. | Weaver, V. | Fadrowski, J.J. | Lin, Y.-S. | Guallar, E. | Navas-Acien, A.
Publication year: 2015
Journal / Book title: Environment International

Access all results for your search in Scopus

High therapeutic potential of positive allosteric modulation of α7 nAChRs in a rat model of traumatic brain injury: Proof-of-concept

Latest UNTHSC Articles in Scopus - Wed, 05/27/2015 - 11:28am
Author(s):Gatson, J.W. | Simpkins, J.W. | Uteshev, V.V.
Publication year: 2015
Journal / Book title: Brain Research Bulletin

Access all results for your search in Scopus
Syndicate content
Contact Us