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Chronic pain and health care spending: an analysis of longitudinal data from the Medical Expenditure Panel Survey.

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Chronic pain and health care spending: an analysis of longitudinal data from the Medical Expenditure Panel Survey.

Health Serv Res. 2015 Jun;50(3):847-70

Authors: Stockbridge EL, Suzuki S, Pagán JA

Abstract
OBJECTIVE: To estimate average incremental health care expenditures associated with chronic pain by health care service category, expanding on prior research that focused on specific pain conditions instead of general pain, excluded low levels of pain, or did not incorporate pain duration.
DATA SOURCE: Medical Expenditure Panel Survey (MEPS) data (2008-2011; N = 26,671).
STUDY DESIGN: Differences in annual expenditures for adults at different levels of pain that interferes with normal work, as measured by the SF-12, were estimated using recycled predictions from two-part logit-generalized linear regression models.
PRINCIPAL FINDINGS: "A little bit" of chronic pain-related interference was associated with a $2,498 increase in total adjusted expenditures over no pain interference (p < .0001) and a $1,008 increase over nonchronic pain interference (p = .0001). Moderate and severe chronic pain-related interference was associated with a $3,707 and $5,804 increase in expenditures over no pain interference and a $2,218 and $4,315 increase over nonchronic interference, respectively (p < .0001). Expenditure increases were most pronounced for inpatient and hospital outpatient expenditures compared to other types of health care expenditures.
CONCLUSIONS: Chronic pain limitations are associated with higher health care expenditures. Results underscore the substantial cost of pain to the health care system.

PMID: 25424348 [PubMed - indexed for MEDLINE]

Fully Threaded Versus Partially Threaded Screws: Determining Shear in Cancellous Bone Fixation.

Fully Threaded Versus Partially Threaded Screws: Determining Shear in Cancellous Bone Fixation.

J Foot Ankle Surg. 2015 Jul 23;

Authors: Downey MW, Kosmopoulos V, Carpenter BB

Abstract
Many researchers have studied and compared various forms of intraosseous fixation. No studies have examined the effects of shear through stiffness and failure strength of a fully threaded versus a partially threaded screw. Our hypothesis was that the fully threaded lag screw technique would provide greater shear strength and resistance. Thirty-six synthetic sawbone blocks were used to test screw fixation. In group 1 (n = 9), 2 blocks were fixed together using a fully threaded 4.0-mm stainless steel cancellous bone screw and the lag technique. In group 2 (n = 8), 2 blocks were fixed together using the standard manufacturer-recommended method for inserting 4.0-mm partially threaded stainless steel cancellous bone screws. The constructs were then mechanically tested. Shear was applied by compressing each construct at an axial displacement rate of 0.5 mm/s until failure. The fully threaded screw had a significantly greater (p = .026) initial stiffness (106.4 ± 15.8 N/mm) than the partially threaded screw (80.1 ± 27.5 N/mm). The yield load and displacement for the fully threaded group (429.4 ± 11.7 N and 7.2 ± 0.35 mm) were 64% and 67% greater than those for the partially threaded screw group (261.4 ± 26.1 N and 4.3 ± 1.03 mm), respectively. The results of the present study have demonstrated the importance of a full-thread construct to prevent shear and to decrease strain at the fracture. The confirmation of our hypothesis questions the future need and use of partially threaded screws for cancellous bone fixation.

PMID: 26210079 [PubMed - as supplied by publisher]

Total testosterone and neuropsychiatric symptoms in elderly men with Alzheimer's disease

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Author(s):Hall, J.R. | Wiechmann, A.R. | Cunningham, R.L. | Johnson, L.A. | Edwards, M. | Barber, R.C. | Singh, M. | Winter, S. | O'Bryant, S.E.
Publication year: 2015
Journal / Book title: Alzheimer's Research and Therapy

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Methylene blue-induced neuronal protective mechanism against hypoxia-reoxygenation stress

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Author(s):Ryou, M.-G. | Choudhury, G.R. | Li, W. | Winters, A. | Yuan, F. | Liu, R. | Yang, S.-H.
Publication year: 2015
Journal / Book title: Neuroscience

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Contra-directional expression of serum homocysteine and uric acid as important biomarkers of multiple system atrophy severity: A cross-sectional study

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Publication year: 2015
Journal / Book title: Frontiers in Cellular Neuroscience

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Motivational tools to improve probationer treatment outcomes

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Author(s):Taxman, F.S. | Walters, S.T. | Sloas, L.B. | Lerch, J. | Rodriguez, M.
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Journal / Book title: Contemporary Clinical Trials

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Acute aerobic exercise mediates G protein-coupled receptor kinase 2 expression in human PBMCs

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Author(s):Huang, C.-J. | Slusher, A.L. | Whitehurst, M. | Wells, M. | Mock, J.T. | Maharaj, A. | Shibata, Y.
Publication year: 2015
Journal / Book title: Life Sciences

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Rhabdomyomatous mesenchymal hamartoma of the face causing trigeminal neuralgia

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Author(s):White, L.R. | Agrawal, V. | Sutton, L. | Balbosa, A.C.
Publication year: 2015
Journal / Book title: American Journal of Case Reports

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Mitochondrial dihydrolipoamide dehydrogenase is upregulated in response to intermittent hypoxic preconditioning

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Author(s):Li, R. | Luo, X. | Wu, J. | Thangthaeng, N. | Jung, M.E. | Jing, S. | Li, L. | Ellis, D.Z. | Liu, L. | Ding, Z. | Forster, M.J. | Yan, L.-J.
Publication year: 2015
Journal / Book title: International Journal of Medical Sciences

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Large-scale recent expansion of European patrilineages shown by population resequencing

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Author(s):Batini, C. | Hallast, P. | Zadik, D. | Delser, P.M. | Benazzo, A. | Ghirotto, S. | Arroyo-Pardo, E. | Cavalleri, G.L. | De Knijff, P. | Dupuy, B.M. | Eriksen, H.A. | King, T.E. | De Munain, A.L. | López-Parra, A.M. | Loutradis, A. | Milasin, J. | Novelletto, A. | Pamjav, H. | Sajantila, A. | Tolun, A. | Winney, B. | Jobling, M.A.
Publication year: 2015
Journal / Book title: Nature Communications

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Therapeutic potential of cancer stem cells

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Author(s):Yang, C. | Jin, K. | Tong, Y. | Cho, W.C.
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Journal / Book title: Medical Oncology

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The effects of sigma (σ1) receptor-selective ligands on muscarinic receptor antagonist-induced cognitive deficits in mice

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Publication year: 2015
Journal / Book title: British Journal of Pharmacology

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Exosomes are unlikely involved in intercellular Nef transfer

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Author(s):Luo, X. | Fan, Y. | Park, I.-W. | He, J.J.
Publication year: 2015
Journal / Book title: PLoS ONE

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Neonatal variables, altitude of residence and Aymara Ancestry in Northern Chile

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Author(s):Rothhammer, F. | Fuentes-Guajardo, M. | Chakraborty, R. | Bermejo, J.L. | Dittmar, M.
Publication year: 2015
Journal / Book title: PLoS ONE

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C-Jun NH<inf>2</inf>-terminal kinase-induced proteasomal degradation of c-FLIP<inf>L/S</inf> and Bcl<inf>2</inf> sensitize prostate cancer cells to Fas- and mitochondria-mediated apoptosis by tetrandrine

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Author(s):Chaudhary, P. | Vishwanatha, J.K.
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Journal / Book title: Biochemical Pharmacology

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Activation of mTOR: A culprit of Alzheimer’s disease?

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Journal / Book title: Neuropsychiatric Disease and Treatment

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Methylene blue protects astrocytes against glucose oxygen deprivation by improving cellular respiration

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Journal / Book title: PLoS ONE

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Coupling between arterial pressure, cerebral blood velocity, and cerebral tissue oxygenation with spontaneous and forced oscillations

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Association of hypothyroidism with low-level arsenic exposure in rural West Texas

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